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In a study involving TAM-resistant cell line MCF-7 tam-R, while 10 6 M TAM has no proliferation inhibitory effect on MCF-7 tam-R, the combined treatment of 10 6 M TAM with ethanol extract of AC was able to increase the effect of TAM to inhibit the proliferation of MCF-7 tam-R cells (Lin et al., 2018)

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GHK-Cu reduces oxidative stress by modulating antioxidant enzyme systems, regulating metal-ion balance, and influencing mitochondrial signaling pathways

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